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Frontier Avalon Angelica , CGC, HIC's Pedigree


 1991 - 2005
OFA RO39233G24F

Information about transitional cell carcinoma (TCC)


 dam of D, E, F litters




Gladlea's Senator of Apoldo 






CH Radio Ranch's Axel von Notara
ARC Gold sire 
CH Rodsden's Nomad vd Harque 
CH Rodsden's Kluge vd Harque, 
CD RO-50 Gold Sire
Rodsden's Gypsy, TD 
CH Kuhlwald's Tara of Ronlyn 
CH Axel vom Schwanenschlag,  
RO-166 Silver Sire
CH Kuhlwald's Little Iodine, CD
CH Rodsden's Vera Du Trier 
CH Max vd Hobertsburg 
Caro v Kupferdach, 
SchH 3
Adda v Dahl, 
SchH 3 
CH Rodsden's Alexa vh Brabant,
CH Falco vh Brabantpark  
RO-286 Gold Sire
CH Rodsden's Lady Luck, CD 
RO-60 Gold Dam

Shadowhaus' Classic Starr



CH Concord's Justin Bear  


Ch. Bethal Farm's Ali   
George Anderson 
CH Graudstark's Irma La Deuce, 
CD RO-752
Concord's Artistic Charm  
Producer Of Merit
CH Welkerhaus' Rommel, UDT  
RO-759-T Gold Sire
Concord's Special Edition 
RO-1899 Bronze Dam
CH Midnight Magic v Shadowhaus  Shadowhaus' Bruno v Meadow CH Rodsden's Bruin v Hungerbuhl, 
CDX RO-1189 Gold Sire
CH Margurita von Meadow, CD 
RO-2184-T Bonze Dam
Altar's Jewel vom Axel   
CH Radio Ranch's Axel von Notara
RO-599 Gold Sire
CH Panamint Yonka v Altar 

2nd place 6-9 puppy 5/31/1992

herdgel  sheepgel

Transitional Cell Carcinoma
Frontier Avalon Angelica CGC, HICs
(November 17, 1991-January 18, 2005)

  In November of 1999 Angelica (aka Gel) broke into the storage closet in the entranceway and destroyed a bottle of windshield washer fluid, consuming some and thus was on medication for minor possible antifreeze poisoning (windshield washer fluid has a minute amount of antifreeze and is minimally toxic). She then had UTI's (urinary tract infections) twice that summer.

In September of 2000 Angelica, then almost 9, had an emergency pyometra spay. The following March 2001 she was VERY ill for a couple weeks with a mystery ailment. She was hospitalized for 5 days. High fever, high white cell count, vomiting, diarrhea etc. If she had not already been spayed the vets would have said pyometra. The final guess was uterine stump pyometra where an infection settles in the remains of the uterine stump. Angelica had a couple more UTI's this summer also.

Over the winter of 2000/2001 Angelica had a couple more UTI's.  When she was first diagnosed (May 2001) with transitional cell carcinoma (TCC) of the bladder, she could only pee in drips -- 1 drop at a time of bloody urine.  At first we thought she had another UTI and tried 1 week of antibiotics to no avail, so we sent off urine for a full exam and culture which is when we discovered the TCC.  Transitional Cell Carcinoma's presence was confirmed with the HUGE clumps of TCC cells in Angelica's urine, as these cell clumps are NOT present unless a TCC tumor is also present.

  Within 2 days of starting Piroxicam she could pee normally and that continued as long as she took her Piroxicam. We opted for no surgery or surgical biopsy based on my research and discussions with others with afflicted dogs and with cancer researchers. TCC spreads like mold spores when touched or cut and thus is a poor type to perform such things on. Also normally bladder cancer is at the part of the bladder away from the outlet and if surgery is performed that portion of the bladder is removed (and most dogs become urine incontinent after surgery). Angelica's is at the exit of the bladder, and thus not eligible for surgery unless we removed most of the bladder and made her 100% incontinent.

We tried Chinese herbs with Gel (started about 1 week post diagnosis), but they made her very very sick as did dog kibble -- the kibble she'd been eating for a good long time. She could not even smell kibble without turning her head away from it!

About 1 month after diagnosis I thought she was dying. Bloody vomit, bloody poop, blood oozing from her vagina, etc.. For several days she was this ill and we seriously considered putting her down. I have since discovered that this "crash" is very common in dogs being given Piroxicam WITHOUT using Sucralfate.  When telling people this story, we now stress that Sucralfate is a must!

We discontinued everything, started her on Sucralfate twice a day and fed her just raw beef burger and amazingly enough, she got better. A couple days later we restarted the Piroxicam and a couple weeks later went to just one Sucralfate a day, 1 hour before her pm meal and Piroxicam. 'Gel' continued to make improvements and moved from death's door to being a normal old Rottweiler.

The average life span of a dog post diagnosis being treated with Piroxicam is 6 months with some living 12 months and a few living longer. Angelica lived 3 years and 8 months post diagnosis!

MOST dogs have had the TCC quite awhile before showing any signs. We guess that Gel had hers for at least 12 months prior, based on her past history of crystals and UTIs (which we had wrongly attributed to her accidental ingestion of windshield washer fluid 2 years prior.)

Angelica was 75-78 pounds and 22 1/2" tall at the shoulder. She took a standard 10 mg capsule of Piroxicam. The actual dosage is 0.3 mg Piroxicam per kilogram of body weight. 10 mg capsules is the norm and some pharmacies will assemble capsules in whatever size you need. Sucralfate comes in a standard 1 gram size and that is what we used.

After the death's door illness, a month after diagnosis, Gel was eating/taking daily the following: (now a days I would use Innova EVO instead of plain Innova, but Evo was not available then)

15 minutes before meal, she got 1 tablespoon Ultraclear Plus mixed with a bit of water (available through Metagenics )
Then we mix together:
1/2 cup ground beef
1/3 can Innova
1000 mg Vitamin C
2 Cranberry capsules dumped into food
10000 IU Vitamin A
200 IU Vitamin E
1 Nutribiotic plus capsule (also available through illnessisoptional) mixed with a bit of warm water

1 hour before hand she got 1 Sucralfate pill - 1gram (prescription med to keep the Piroxicam from eating her stomach)
Then 15 minutes before meal she got 2 tablespoons Ultraclear Plus mixed with a bit of water
Then we mix together:
1/2 cup ground beef
1/3 can Innova
1000 mg Vitamin C
2 cranberry capsules dumped into food
1/2 human multi-vitamin with no colors added
followed by 10 mg Piroxicam (the dosage is about 0.3 mg/kg) and a slice of bread (her treat)

In April of 2003, we changed her from the ground beef to Bravo prepared raw beef (meat, ground bone & veggies) 8 ounces in the morning and 6 ounces in the evening and 1/4 can Innova.

In November of 2004 we changed to less Innova canned and added some Innova EVO dry food in an effort to reduce carbs further and she tolerated this well.

After diagnosis, she got no vaccines at all except Rabies. No chemicals applied or ingested.  At each of her recheck urinalysis the clumps of TCC cells became less and less and about a year before her death they only saw scattered TCC cells, not clumps.

Some of the websites I have utilized:

from the pub med website
articles # PMID: 11809678
PMID: 7653891
PMID: 7983623
PMID: 1733554

Marvistavet on Piroxicam use for TCC

Marvistavet on TCC

Marvistavet on Sucralfate

Rennie’s page of TCC resources

  Angelica collapsed on her way in from going out for her last potty at 11 p.m. on January 17, 2005 and then managed to get in the house without aide. She and I and our then almost 2-year old Rottweiler Bea stayed on her bed with her most of the night and she passed in her sleep after 1:00 a.m. on the 18th of January, 2005. Angelica was 13 years 2 months old. A WONDERFUL dog to the end.



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Transitional Cell Carcinoma
our TCC journey with Angelica

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Diane Richardson
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Last updated 6/20/23
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